Vaginal delivery system for cattle

COMPOSITION: progesterone 1,55 g per device.

INDICATIONS: For the control of the oestrus cycle in cows and heifers including: Synchronization of oestrus in cycling cattle. To be used in combination with a prostaglandin (pGF2). Induction and synchronization of oestrus in non-cycling cattle. To be used in combination with a prostaglandin and equine Chorionic Gonadotropin (eCG, in the past called pMSG).

CONTRAINDICATIONS: Do not use in sexually immature heifers. Do not use before 35 days have passed since previous calving. Do not use in animals suffering from infectious or non-infectious disease of the genital tract. Do not use in pregnant animals. See section Use during pregnancy and lactation.

ADVERSE REACTIONS: During the course of the seven day treatment, the device may induce a mild local reaction (i.e. inflammation of the vaginal wall). A clinical study carried out with 319 cows and heifers has demonstrated that a 25% of animals presented ropy or cloudy vulvar secretions at the removal of the device. This local reaction disappears rapidly without any treatment between removal and insemination and does not affect fertility at inseminations nor pregnancy rates. If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary.

DOSAGE, ROUTE AND METHOD OF ADMINISTRATION: Vaginal use. 1.55 g of progesterone / animal for 7 days. Using an applicator, insert a device into the vagina of the animal. The intravaginal device should stay in place for 7 days. In cycling cattle, the device has to be used in combination with a prostaglandin, injected 24 hours prior to the removal of the device. In non-cycling cattle, an injection of a prostaglandin must be performed 24 hours prior to the removal of the device and an injection of eCG at the time of removal. The device is intended for single use only.

WITHDRAWAL PERIOD: Meat and offal: zero days. Milk: zero days. During the treatment meat, offal and milk can be delivered for human consumption CATEGORY: List II. POMV.

PRESENTATIONS: Cardboard box containing 10 sachets with 1 device each. Polyethylene box containing 50 sachets with 1 device each. Sachet containing 10 devices.